SCHEMBL16828131

SCHEMBL16828131

c1ccc(-n2ccc3ccc4c5ccccc5ccc4c32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 4/20 0.50
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
CYP2A6 P11509 1/20 0.43
TSHR P16473 1/20 0.43
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
NPSR1 Q6W5P4 1/20 0.39
PAX8 Q06710 1/20 0.38
HIF1A Q16665 2/20 0.38
CYP1B1 Q16678 1/20 0.38
HTR2A P28223 2/20 0.37
HTR2C P28335 1/20 0.37
LMNA P02545 2/20 0.36
MAPK1 P28482 2/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
APEX1 P27695 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1177890 0.91 HTR2A (0.44) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL15802181 0.82 CDK4 (0.36) HPRT1ALDH1A1HSD17B10TSHRNPSR1
Piperazine SCHEMBL28875077 0.81 HTR2A (0.39) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL17015339 0.79 CYP1A2 (0.40) HPRT1ALDH1A1HSD17B10TDP1CYP1A2
SCHEMBL17015337 0.79 KDM4E (0.39) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL30960426 0.78 DDB1 (0.42) ALDH1A1HSD17B10TDP1TSHRCYP2C9
SCHEMBL15801739 0.78 KDM4E (0.45) NPSR1BIRC5
SCHEMBL15802359 0.78 KDM4E (0.45) NPSR1BIRC5
SCHEMBL15213666 0.77 KDM4E (0.52) ALDH1A1MAPK1MAPTBIRC5MEN1
SCHEMBL22404031 0.76 ALDH1A1 (0.37) ALDH1A1TDP1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015093818-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME 주식회사 두산 2015-06-25 WO disclosed
WO-2015093818-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME 주식회사 두산 2015-06-25 WO disclosed