SCHEMBL16828142

SCHEMBL16828142

[CH2]C(O)CC(C)N1CCOCC1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 4/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CYP3A4 P08684 2/20 0.33
CYP2C19 P33261 2/20 0.33
KCNA5 P22460 1/20 0.33
GAA P10253 2/20 0.32
PKM P14618 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9801619 0.83 USP2 (0.40) USP2KMT2AMEN1ALDH1A1LMNA
SCHEMBL19057143 0.79 KMT2A (0.41) USP2KMT2AMEN1ALDH1A1LMNA
SCHEMBL19472816 0.79 KMT2A (0.41) USP2KMT2AMEN1ALDH1A1LMNA
SCHEMBL9801362 0.77 KMT2A (0.40) USP2KMT2AMEN1ALDH1A1LMNA
SCHEMBL19168565 0.75 KMT2A (0.39) USP2KMT2AMEN1ALDH1A1LMNA
SCHEMBL1477384 0.74 KMT2A (0.41) USP2KMT2AMEN1ALDH1A1LMNA
SCHEMBL295997 0.74 KMT2A (0.41) USP2KMT2AMEN1ALDH1A1LMNA
SCHEMBL19285734 0.74 KMT2A (0.41) USP2KMT2AMEN1ALDH1A1LMNA
SCHEMBL300143 0.74 KMT2A (0.41) USP2KMT2AMEN1ALDH1A1LMNA
SCHEMBL14856607 0.74 KMT2A (0.41) USP2KMT2AMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3300720-B1 PERSONAL CARE COMPOSITIONS WITH MODIFIED GUAR DERIVATIVES ROHM & HAAS (US) 2020-08-26 EP claimed
EP-3300720-B1 PERSONAL CARE COMPOSITIONS WITH MODIFIED GUAR DERIVATIVES ROHM & HAAS (US) 2020-08-26 EP disclosed
US-10123961-B2 Personal care compositions with modified guar derivatives ROHM & HAAS COMPANY (US) 2018-11-13 US disclosed
EP-3300720-A1 PERSONAL CARE COMPOSITIONS WITH MODIFIED GUAR DERIVATIVES Rohm and Haas Company (US) 2018-04-04 EP disclosed
EP-3082756-B1 PERSONAL CARE COMPOSITIONS WITH MODIFIED GUAR DERIVATIVES ROHM & HAAS (US) 2018-01-31 EP disclosed
US-20160310401-A1 PERSONAL CARE COMPOSITIONS WITH MODIFIED GUAR DERIVATIVES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC 2016-10-27 US disclosed
EP-3082756-A1 PERSONAL CARE COMPOSITIONS WITH MODIFIED GUAR DERIVATIVES Rohm and Haas Company (US) 2016-10-26 EP disclosed
WO-2015095677-A1 PERSONAL CARE COMPOSITIONS WITH MODIFIED GUAR DERIVATIVES ROHM AND HAAS CHEMICALS LLC (US) 2015-06-25 WO disclosed