Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16828215 | 0.89 | CDK1 (0.31) | CCNA2CDK2CCNA1NUDT1CDK1 | |
| SCHEMBL16828162 | 0.84 | CCNA2 (0.50) | CCNA2CDK2CCNA1NUDT1TLR8 | |
| SCHEMBL16828159 | 0.83 | CCNA2 (0.40) | CCNA2CDK2CCNA1NUDT1TLR8 | |
| SCHEMBL16852182 | 0.83 | SMN1; SMN2 (0.36) | CCNA2CDK2CCNA1NUDT1CDK1 | |
| Hydrochloric Acid SCHEMBL16828222 | 0.82 | CCNA2 (0.48) | CCNA2CDK2CCNA1NUDT1TLR8 | |
| SCHEMBL16828186 | 0.82 | CCNA2 (0.39) | CCNA2CDK2CCNA1NUDT1TLR8 | |
| SCHEMBL16828209 | 0.80 | CDK1 (0.49) | CCNA2CDK2CCNA1TLR8TLR7 | |
| SCHEMBL16828244 | 0.80 | CDK1 (0.49) | CCNA2CDK2CCNA1TLR8TLR7 | |
| SCHEMBL16828240 | 0.79 | CDK1 (0.50) | CCNA2CDK2CCNA1TLR8CDK1 | |
| SCHEMBL16828189 | 0.79 | CCNA2 (0.37) | CCNA2CDK2CCNA1TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9636288-B2 | Means for oxidative dyeing of keratin fibers containing novel tetra-substituted derivatives of pyrimidine | HENKEL AG & CO. KGAA (DE) | 2017-05-02 | — | — | US | disclosed |
| US-9636288-B2 | Means for oxidative dyeing of keratin fibers containing novel tetra-substituted derivatives of pyrimidine | HENKEL AG & CO. KGAA (DE) | 2017-05-02 | — | — | US | disclosed |
| EP-3082751-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | Henkel AG & Co. KGaA (DE) | 2016-10-26 | — | — | EP | disclosed |
| US-20160296447-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | HENKEL AG & CO. KGAA (DE) | 2016-10-13 | — | — | US | disclosed |
| US-20160296447-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | HENKEL AG & CO. KGAA (DE) | 2016-10-13 | — | — | US | disclosed |
| WO-2015090292-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015090292-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | HENKEL AG & CO. KGAA (DE) | 2015-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160296447-A1 | MEANS FOR OXIDATIVE DYEING OF KERATIN FIBERS CONTAINING NOVEL TETRA-SUBSTITUTED DERIVATIVES OF PYRIMIDINE | KRT18, TK1, DPYD | CCNA2 732/4885CDK2 1433/4885CCNA1 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.