Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282641 | 0.92 | ABL1 (0.38) | ABL1PIK3CAPIK3CG | |
| SCHEMBL1684969 | 0.91 | ABL1 (0.36) | ABL1PIK3CAPIK3CG | |
| SCHEMBL1282638 | 0.91 | ABL1 (0.37) | ABL1PIK3CAPIK3CG | |
| SCHEMBL1282186 | 0.91 | ABL1 (0.37) | ABL1PIK3CAPIK3CG | |
| SCHEMBL1282787 | 0.91 | ABL1 (0.37) | ABL1PIK3CAPIK3CG | |
| SCHEMBL1282255 | 0.91 | ABL1 (0.37) | ABL1PIK3CG | |
| SCHEMBL1281952 | 0.90 | ABL1 (0.36) | ABL1 | |
| SCHEMBL1282074 | 0.90 | ABL1 (0.36) | ABL1 | |
| SCHEMBL1282716 | 0.89 | ABL1 (0.37) | ABL1PIK3CAPIK3CG | |
| SCHEMBL1283247 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012045124-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | BIOTA EUROPE LTD (GB) | 2012-04-12 | — | — | WO | disclosed |