Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283035 | 0.91 | ABL1 (0.37) | ABL1PIK3CGPIK3CANPC1RAB9A | |
| SCHEMBL1682886 | 0.91 | ABL1 (0.37) | ABL1PIK3CGPIK3CA | |
| SCHEMBL1282693 | 0.89 | ABL1 (0.35) | ABL1PIK3CGPIK3CANPC1RAB9A | |
| SCHEMBL1282944 | 0.89 | ABL1 (0.37) | ABL1PIK3CGPIK3CA | |
| SCHEMBL1282855 | 0.89 | ABL1 (0.36) | ABL1PIK3CGPIK3CA | |
| SCHEMBL1282609 | 0.89 | ABL1 (0.35) | ABL1PIK3CGPIK3CA | |
| SCHEMBL1282707 | 0.86 | ABL1 (0.35) | ABL1PIK3CGPIK3CA | |
| SCHEMBL1282741 | 0.86 | ABL1 (0.34) | ABL1PIK3CGPIK3CA | |
| SCHEMBL1282740 | 0.86 | ABL1 (0.34) | ABL1PIK3CGPIK3CA | |
| SCHEMBL1684137 | 0.85 | ABL1 (0.33) | ABL1PIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012045124-A1 | BACTERIA TOPOISOMERASE II INHIBITING 2-ETHYLCARBAMOYLAMINO-1, 3-BENZOTHIAZOL-5-YLS | BIOTA EUROPE LTD (GB) | 2012-04-12 | — | — | WO | disclosed |