Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20144010 | 1.00 | NOTUM (0.41) | NOTUMSMN1; SMN2TP53HRH3MITF | |
| SCHEMBL13378227 | 0.91 | — | — | |
| SCHEMBL12009713 | 0.82 | — | — | |
| SCHEMBL22485710 | 0.79 | — | — | |
| SCHEMBL20242724 | 0.78 | LMNA (0.33) | SMN1; SMN2MITFLMNA | |
| SCHEMBL8379280 | 0.77 | SMN1; SMN2 (0.50) | NOTUMSMN1; SMN2TP53MITFKDM4E | |
| SCHEMBL15071000 | 0.77 | SMN1; SMN2 (0.50) | NOTUMSMN1; SMN2TP53MITFKDM4E | |
| SCHEMBL18566 | 0.77 | SMN1; SMN2 (0.50) | NOTUMSMN1; SMN2TP53MITFKDM4E | |
| SCHEMBL15061890 | 0.77 | SMN1; SMN2 (0.50) | NOTUMSMN1; SMN2TP53MITFKDM4E | |
| SCHEMBL15061902 | 0.77 | SMN1; SMN2 (0.50) | NOTUMSMN1; SMN2TP53MITFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9062153-B2 | Compositions, preparation thereof and use thereof for production of cast polyamides | RHEIN CHEMIE RHEINAU GMBH (DE) | 2015-06-23 | — | — | US | disclosed |