Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | CNR1 | P21554 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076702 | 0.94 | THRB (0.62) | THRBTP53MAPTSMN1; SMN2CNR1 | |
| SCHEMBL16903056 | 0.93 | TP53 (0.62) | TP53MAPTSMN1; SMN2CNR1CNR2 | |
| SCHEMBL15076358 | 0.91 | CYP3A4 (0.59) | TP53MAPTSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL21623135 | 0.91 | CYP3A4 (0.59) | TP53MAPTSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL16903055 | 0.90 | TP53 (0.63) | THRBTP53MAPTSMN1; SMN2CNR1 | |
| SCHEMBL19157334 | 0.90 | THRB (0.60) | THRBTP53MAPTSMN1; SMN2CNR1 | |
| SCHEMBL21625036 | 0.88 | CYP3A4 (0.62) | THRBTP53MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL15076495 | 0.88 | CYP1A2 (0.56) | TP53MAPTSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL21623562 | 0.88 | CYP3A4 (0.62) | THRBTP53MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL18085481 | 0.87 | TP53 (0.65) | THRBTP53MAPTSMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9061008-B2 | Hepatitis B antiviral agents | NOVIRA THERAPEUTICS, INC. (US) | 2015-06-23 | — | — | US | disclosed |