SCHEMBL168392

SCHEMBL168392

Cc1cc(C(C)(C)C)c(N)cc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.48
TSHR P16473 3/20 0.48
MAPK1 P28482 2/20 0.48
ALDH1A1 P00352 7/20 0.44
CYP1A2 P05177 3/20 0.44
ALOX15 P16050 3/20 0.44
HIF1A Q16665 2/20 0.44
HSD17B10 Q99714 2/20 0.44
CASP7 P55210 1/20 0.44
POLB P06746 2/20 0.41
TERT O14746 1/20 0.38
TDP1 Q9NUW8 3/20 0.37
CASP1 P29466 1/20 0.37
AR P10275 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
CA2 P00918 1/20 0.36
TYR P14679 1/20 0.36
KDM4E B2RXH2 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30301248 1.00 CYP3A4 (0.48) CYP3A4TSHRMAPK1ALDH1A1CYP1A2
SCHEMBL10385743 0.90 CYP3A4 (0.55) CYP3A4TSHRMAPK1ALDH1A1CYP1A2
SCHEMBL24910873 0.87 CYP3A4 (0.50) CYP3A4TSHRMAPK1ALDH1A1CYP1A2
SCHEMBL22367815 0.87 CYP3A4 (0.50) CYP3A4TSHRMAPK1ALDH1A1CYP1A2
SCHEMBL560086 0.84 PTK2 (0.41) TSHRALDH1A1CYP1A2ALOX15HSD17B10
SCHEMBL2153631 0.81 ALDH1A1 (0.43) CYP3A4TSHRMAPK1ALDH1A1CYP1A2
SCHEMBL28274470 0.80 F2 (0.45) CYP3A4TSHRMAPK1ALDH1A1CYP1A2
SCHEMBL15501699 0.80 CYP3A4 (0.42) CYP3A4TSHRMAPK1ALDH1A1CYP1A2
SCHEMBL24116135 0.80 CYP3A4 (0.55) CYP3A4TSHRMAPK1ALDH1A1CYP1A2
SCHEMBL15927489 0.79 CYP3A4 (0.42) CYP3A4TSHRMAPK1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9827646-B2 Polishing pad and preparing method thereof FNS TECH CO., LTD. (KR) 2017-11-28 US claimed
CN-106670990-A Porous polishing pad and preparing method of the same FNS科技有限公司 2017-05-17 CN claimed
US-20170129072-A1 Porous Polishing Pad and Preparing Method of the Same FNS TECH CO., LTD. (KR) 2017-05-11 US claimed
US-20160339559-A1 POLISHING PAD AND PREPARING METHOD THEREOF FNS Tech. Co., Ltd. (KR) 2016-11-24 US claimed
EP-2220034-B1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE SIKA TECHNOLOGY AG (CH) 2015-12-23 EP claimed
US-9150494-B2 Process using microchannel technology for conducting alkylation or acylation reaction VELOCYS, INC. (US) 2015-10-06 US claimed
US-8668986-B2 Aromatic aldimines and polyurethane compositions which contain aldimine SIKA TECHNOLOGY AG (CH) 2014-03-11 US claimed
US-8431489-B2 Chemical mechanical polishing pad having a low defect window ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. (US) 2013-04-30 US claimed
US-20120295442-A1 Chemical mechanical polishing pad having a low defect window ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. (US) 2012-11-22 US claimed
US-8257544-B2 Chemical mechanical polishing pad having a low defect integral window ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. (US) 2012-09-04 US claimed
US-5096956-A Dispersion with aromatic diamines, fatty acid metal salt in aliphatic amine; polyetheruretane by reaction injection molding; fenders, bumpers SUMITOMO BAYER URETHANE CO., LTD. (JP) 1992-03-17 US claimed
US-4973660-A Polyamide of diamino-t-butyltoluene AMOCO CORPORATION (US) 1990-11-27 US claimed
US-4963648-A SOLVENT-SOLUBLILITY; HEAT RESISTANCE; FILMS, FIBERS, COMPOSITES; ELECTRICAL APPARATUS; AROMATIC POLYAMIDES AMOCO CORPORATION (US) 1990-10-16 US claimed
EP-0177916-B1 MONO-TERTIARY-ALKYLATED TOLUENEDIAMINE AND DERIVATIVES AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-04-11 EP claimed
EP-0178583-B1 POLYURETHANE SYSTEMS USING MONOTERTIARY-ALKYLTOLUENEDIAMINE AS A CROSS LINKER AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-05-31 EP claimed
US-4816543-A REACTIN INJECTION MOLDING MATERIALS AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-03-28 US claimed
US-4745223-A CHAIN EXTENDERS FOR POLYUREAS AND POLYURETHANES AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-05-17 US claimed
US-4693837-A Tertiary butyl derivatives of toluenediamine and mixtures as antioxidant for organic materials AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-09-15 US claimed
EP-0178583-A1 Polyurethane systems using monotertiary-alkyltoluenediamine as a cross linker AIR PRODUCTS AND CHEMICALS, INC. (US) 1986-04-23 EP claimed
EP-0177916-A1 Mono-tertiary-alkylated toluenediamine and derivatives AIR PRODUCTS AND CHEMICALS, INC. (US) 1986-04-16 EP claimed