Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | FDPS | P14324 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.56 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.56 |
| ▸ | ABAT | P80404 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.56 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13644446 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL13521532 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL30271611 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL10031796 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL29101754 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL25228293 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL29452432 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL11545585 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL16839642 | 0.79 | DRD1 (0.46) | ALDH1A1TSHRFDPSHPGDTRIM24 | |
| SCHEMBL21159060 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TSHRFDPSHPGDTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150175541-A1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175541-A1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | EGLN2, EGLN3, EGLN1 | ALDH1A1 2293/4885TSHR 3613/4885FDPS 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.