⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5245144 | 0.97 | KDM4E (0.60) | — | |
| SCHEMBL1031783 | 0.97 | KDM4E (0.60) | — | |
| SCHEMBL63826 | 0.97 | KDM4E (0.60) | — | |
| Hydrochloric Acid SCHEMBL73679 | 0.97 | KDM4E (0.60) | — | |
| Hydrochloric Acid SCHEMBL2673610 | 0.95 | KDM4E (0.58) | — | |
| Hydrochloric Acid SCHEMBL7527100 | 0.95 | KDM4E (0.58) | — | |
| SCHEMBL1259867 | 0.94 | — | — | |
| SCHEMBL23014621 | 0.92 | KDM4E (0.60) | — | |
| SCHEMBL7748218 | 0.92 | KDM4E (0.60) | — | |
| SCHEMBL6174155 | 0.91 | KDM4E (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301736-B1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2025-10-08 | — | — | EP | claimed |
| EP-4619106-A2 | TREATMENT OF ASCT2-DEPENDENT CANCERS | Neupharma, Inc (US) | 2025-09-24 | — | — | EP | claimed |
| CN-119798223-A | (1H-indazol-5-yl) amino-2-pyridine derivative and application thereof | 沈阳药科大学 | 2025-04-11 | — | — | CN | claimed |
| US-20240415819-A1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | QLi5 Therapeutics AG (DE) | 2024-12-19 | — | — | US | claimed |
| WO-2024107753-A2 | TREATMENT OF ASCT2-DEPENDENT CANCERS | NEUPHARMA, INC (US) | 2024-05-23 | — | — | WO | claimed |
| CN-112020356-B | Combination of quinoline-4-carboxamides and benzonaphthyridine derivatives as antimalarial drug combinations | 默克专利股份有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-115785070-B | Pyrrolidinyl acetamide derivative, preparation method and application thereof | 桂林医学院附属医院 | 2023-06-09 | — | — | CN | claimed |
| EP-4155296-A1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | Lead Discovery Center GmbH (DE) | 2023-03-29 | — | — | EP | claimed |
| CN-115785070-A | Pyrrolidinylacetamide derivative, preparation method and application thereof | 桂林医学院附属医院 | 2023-03-14 | — | — | CN | claimed |
| US-11542265-B2 | Pyrazolopyrimidine compounds and uses thereof | INCYTE CORPORATION (US) | 2023-01-03 | — | — | US | claimed |
| US-5461157-A | Process for preparing pyrrolidinylacetamide derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | claimed |
| EP-0434943-B1 | Polyene macrolide derivatives | PRODOTTI ANTIBIOTICI SPA (IT) | 1995-09-06 | — | — | EP | claimed |
| CN-1085893-A | Process for preparing pyrrolidinylacetamide derivatives | DAIICHI SEIYAKU CO (JP) | 1994-04-27 | — | — | CN | claimed |
| US-5296597-A | Antibiotics | SPA SOCIETA' PRODOTTI ANTIBIOTICI S.P.A. (IT) | 1994-03-22 | — | — | US | claimed |
| EP-0574952-A1 | Process for preparing 2-oxopyrrolidinylacetamide derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-12-22 | — | — | EP | claimed |
| EP-0434943-A1 | Polyene macrolide derivatives | S P A SOCIETA' PRODOTTI ANTIBIOTICI S.p.a. (IT) | 1991-07-03 | — | — | EP | claimed |
| EP-0408782-A1 | Antihypoxic agent | NAUCHNOISSLEDOVATELSKI CHIMIKOPHARMATZEVTICHEN INSTITUT (BG) | 1991-01-23 | — | — | EP | claimed |
| US-4939126-A | 1-pyrrolidineacetamide derivatives and use thereof | SANWA KAGAKU KENKYUSHO CO. LTD. (JP) | 1990-07-03 | — | — | US | claimed |
| EP-0299495-A2 | 1-Pyrrolidineacetamide derivatives and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-01-18 | — | — | EP | claimed |
| US-4122265-A | APPETITE SUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1978-10-24 | — | — | US | claimed |