Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.31 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630345 | 0.85 | GDA (0.37) | GDAPARP1GAAPNP | |
| SCHEMBL453562 | 0.82 | POLB (0.44) | HSD17B10GAAKDM4EPDPK1 | |
| SCHEMBL8506347 | 0.81 | GDA (0.34) | GDA | |
| SCHEMBL8505965 | 0.80 | GDA (0.33) | GDA | |
| SCHEMBL27473136 | 0.79 | GABRR1 (0.35) | GDACYP2C19HSD17B10PARP1GAA | |
| SCHEMBL9393663 | 0.79 | ADORA2A (0.46) | GDAGAA | |
| SCHEMBL20508956 | 0.77 | TDP1 (0.37) | GAAKMT2A | |
| SCHEMBL5694198 | 0.76 | ALOX15 (0.40) | GAAKDM4EKMT2A | |
| SCHEMBL8592141 | 0.76 | CYP1A2 (0.44) | GDACYP2C19HSD17B10PARP1GAA | |
| SCHEMBL8581230 | 0.75 | KMT2A (0.45) | KDM4EKMT2AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000036-B2 | Compositions and methods for targeting of treating neoplasms | Yu, Baofa (US) | 2015-04-07 | — | — | US | disclosed |
| US-20140037695-A1 | COMPOSITIONS AND METHODS FOR TARGETING OF TREATING NEOPLASMS | YU, BAOFA | 2014-02-06 | — | — | US | disclosed |
| US-8501243-B2 | Targeting cancer therapy combination | YU, BAOFA | 2013-08-06 | — | — | US | disclosed |
| US-7927612-B2 | Mixture of an oxidizing agent or a reducing agent, a protein denaturing agent, and a hapten; can be used with other anticancer treatments such as radiotherapy, chemotherapy; coagulate tumors and enhance inflammatory response against systemic tumors at multiple sites | Yu, Baofa (US) | 2011-04-19 | — | — | US | disclosed |
| US-20100104660-A1 | COMPOSITION AND METHOD FOR TREATING TUMOR | YU, BAOFA | 2010-04-29 | — | — | US | disclosed |
| CN-101138634-A | Composition for treating tumour | BAOFA YU (CN) | 2008-03-12 | — | — | CN | disclosed |
| CN-1273146-C | Composition for treating tumor | YU BAOFA (US) | 2006-09-06 | — | — | CN | disclosed |
| US-20050118187-A1 | Combinations and methods for treating neoplasms | YU, BAOFA | 2005-06-02 | — | — | US | disclosed |
| US-6811788-B2 | ONE OR MORE HAPTENS AND COAGULATION AGENTS OR TREATMENTS, ALONE OR IN COMBINATION WITH OTHER ANTI-NEOPLASTIC AGENTS OR TREATMENTS | Yu, Baofa | 2004-11-02 | — | — | US | disclosed |
| CN-1431909-A | Combinations for treating neoplasms | YU BAOFA (US) | 2003-07-23 | — | — | CN | disclosed |