Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027924 | 0.84 | GABRR1 (0.34) | BTN3A1 | |
| SCHEMBL9364993 | 0.84 | GABRR1 (0.34) | BTN3A1 | |
| SCHEMBL5027923 | 0.84 | GABRR1 (0.34) | BTN3A1 | |
| SCHEMBL26478528 | 0.82 | — | — | |
| SCHEMBL30664718 | 0.82 | — | — | |
| SCHEMBL2670209 | 0.81 | BTN3A1 (0.35) | BTN3A1 | |
| SCHEMBL1751319 | 0.81 | BTN3A1 (0.35) | BTN3A1 | |
| SCHEMBL2670343 | 0.81 | BTN3A1 (0.35) | BTN3A1 | |
| SCHEMBL22025160 | 0.79 | — | — | |
| SCHEMBL16820643 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150175530-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175530-A1 | ANTIBACTERIAL AGENTS | MRPL21, ABCB11, LSS | TSHR 4007/4885BTN3A1 4422/4885MAPT 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.