SCHEMBL16842425

SCHEMBL16842425

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccc5c6cccc7c8ccccc8n(c5c4)c76)ccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
ATM Q13315 1/20 0.49
KMT2A Q03164 4/20 0.36
HDAC4 P56524 1/20 0.36
PTGER4 P35408 1/20 0.34
EDNRB P24530 1/20 0.34
EDNRA P25101 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 3/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
TSPO P30536 1/20 0.33
IL1R1 P14778 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
PTPN1 P18031 2/20 0.32
PPARG P37231 1/20 0.31
MAPK8 P45983 1/20 0.31
GAA P10253 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16842483 0.99 KDM4E (0.47) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL16842476 0.99 KDM4E (0.47) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL16842503 0.99 KDM4E (0.47) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL16842524 0.99 KDM4E (0.47) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL16842536 0.99 KDM4E (0.47) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL16842551 0.99 KDM4E (0.47) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL16842481 0.97 KDM4E (0.46) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL16842496 0.97 KDM4E (0.46) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL17146769 0.97 KDM4E (0.46) KDM4EL3MBTL1ATMKMT2AHDAC4
SCHEMBL16842480 0.97 L3MBTL1 (0.46) KDM4EL3MBTL1ATMKMT2AHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4186898-A1 COMPOSITION FOR ORGANIC ELECTRONIC COMPOUNDS Merck Patent GmbH (DE) 2023-05-31 EP disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
EP-3649213-B1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-06-23 EP disclosed
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-23 US disclosed
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-09 US disclosed
WO-2019233904-A1 ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2019-12-12 WO disclosed
WO-2019007867-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-01-10 WO disclosed
US-9929353-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-03-27 US disclosed
US-9929353-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-03-27 US disclosed
EP-2927234-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2016-09-28 EP disclosed
US-20150287933-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-10-08 US disclosed
US-20150287933-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-10-08 US disclosed
EP-2927234-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2015-10-07 EP disclosed
US-20150179949-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-25 US disclosed
US-20150179949-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO4C1, SLCO2A1 KDM4E 3376/4885L3MBTL1 3718/4885ATM 4360/4885
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 KDM4E 3745/4885L3MBTL1 3258/4885ATM 4632/4885
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 KDM4E 3745/4885L3MBTL1 3258/4885ATM 4632/4885
US-20150287933-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, JUND KDM4E 2566/4885L3MBTL1 1043/4885ATM 3633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.