Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | PIK3C2B | O00750 | 5/20 | 0.37 |
| ▸ | BTK | Q06187 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16806465 | 0.87 | PIK3CD (0.43) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL16783850 | 0.87 | PIK3CD (0.43) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL16783619 | 0.76 | PIK3CD (0.49) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL16843404 | 0.76 | PIK3CD (0.49) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL21327907 | 0.75 | PIK3CD (0.42) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C2B | |
| SCHEMBL16783770 | 0.73 | PIK3C2B (0.59) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C2B | |
| SCHEMBL16783876 | 0.72 | PIK3CD (0.53) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL21327912 | 0.72 | PIK3CD (0.53) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL16806471 | 0.72 | PIK3CD (0.53) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL16806454 | 0.71 | PIK3CD (0.49) | PIK3CGPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015091685-A1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-06-25 | — | — | WO | disclosed |