Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | PIK3C2B | O00750 | 3/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16783729 | 0.88 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL21327910 | 0.88 | PIK3CD (0.41) | PIK3CDPIK3CGPIK3CBPIK3CATGFBR1 | |
| SCHEMBL16806454 | 0.83 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL16783576 | 0.81 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL16825635 | 0.80 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3CBPIK3CABTK | |
| SCHEMBL16843367 | 0.80 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| Formic Acid SCHEMBL16783472 | 0.79 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3CBPIK3CA | |
| SCHEMBL16783887 | 0.78 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3CBPIK3CABTK | |
| Formic Acid SCHEMBL16783669 | 0.78 | PIK3CD (0.45) | PIK3CDPIK3CGPIK3CBPIK3CABTK | |
| SCHEMBL16783831 | 0.78 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3CBPIK3CABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083617-B1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2019-09-11 | — | — | EP | disclosed |