Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675687 | 1.00 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL28672736 | 1.00 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL28690397 | 1.00 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL15943067 | 0.98 | TSHR (0.61) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL8432394 | 0.91 | TSHR (0.64) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL28075111 | 0.90 | L3MBTL1 (0.53) | TSHRL3MBTL1LMNAPPARGKMT2A | |
| SCHEMBL15841865 | 0.89 | L3MBTL1 (0.49) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL28709667 | 0.87 | TSHR (0.58) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL15994316 | 0.85 | TSHR (0.56) | TSHRL3MBTL1LMNAALDH1A1PABPC1 | |
| SCHEMBL17883542 | 0.85 | TSHR (0.56) | TSHRL3MBTL1LMNAALDH1A1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2886530-A1 | ORALLY ADMINISTRABLE VIRIDIOFUNGIN DERIVATIVE HAVING ANTI-HCV ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 2015-06-24 | — | — | EP | disclosed |