⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3667680 | 0.94 | PGR (0.65) | — | |
| SCHEMBL16845457 | 0.90 | PGR (0.56) | — | |
| SCHEMBL16845463 | 0.90 | PGR (0.58) | — | |
| SCHEMBL2218597 | 0.89 | AR (0.66) | — | |
| SCHEMBL7785957 | 0.88 | AR (0.66) | — | |
| SCHEMBL26451505 | 0.87 | AR (0.65) | — | |
| SCHEMBL16841792 | 0.87 | IGF1R (0.49) | — | |
| SCHEMBL16845631 | 0.87 | AR (0.65) | — | |
| SCHEMBL4028958 | 0.86 | AR (0.67) | — | |
| SCHEMBL2216153 | 0.86 | AR (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682960-B2 | Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety | ENDORECHERCHE, INC. (CA) | 2017-06-20 | — | — | US | disclosed |
| WO-2015089634-A9 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | ENDORECHERCHE, INC. (CA) | 2016-01-14 | — | — | WO | disclosed |
| WO-2015089634-A1 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | ENDORECHERCHE, INC. (CA) | 2015-06-25 | — | — | WO | disclosed |
| US-20150175576-A1 | NON-STEROIDAL ANTIANDROGENS AND SELECTIVE ANDROGEN RECEPTOR MODULATORS WITH A PYRIDYL MOIETY | ENDORECHERCHE, INC. (CA) | 2015-06-25 | — | — | US | disclosed |