Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.56 |
| ▸ | KDR | P35968 | 16/20 | 0.56 |
| ▸ | IGF1R | P08069 | 14/20 | 0.56 |
| ▸ | MST1R | Q04912 | 2/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | INSR | P06213 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FES | P07332 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | LYN | P07948 | 1/20 | 0.54 |
| ▸ | RET | P07949 | 1/20 | 0.54 |
| ▸ | FGR | P09769 | 1/20 | 0.54 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10268945 | 0.90 | MET (0.54) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL723553 | 0.89 | MET (0.61) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL16817169 | 0.79 | MET (0.48) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL12786992 | 0.75 | MET (0.59) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL25232067 | 0.73 | MET (0.58) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL30227696 | 0.73 | MET (0.58) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL198269 | 0.72 | MET (0.73) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL199079 | 0.72 | MET (1.00) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL29383141 | 0.72 | MET (1.00) | METKDRIGF1RMST1RAURKA | |
| SCHEMBL21097756 | 0.71 | MET (0.84) | METKDRIGF1RMST1RAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609100-B1 | FUROPYRIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-06-24 | — | — | EP | disclosed |