Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18107164 | 1.00 | CYP11B1 (0.49) | CYP11B1CYP11B2 | |
| SCHEMBL18107156 | 0.81 | CYP11B1 (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL16847894 | 0.81 | CYP11B1 (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL14143257 | 0.79 | CYP2C19 (0.38) | CYP11B1CYP11B2 | |
| SCHEMBL16834839 | 0.79 | CYP11B1 (0.49) | CYP11B1CYP11B2 | |
| SCHEMBL16834838 | 0.79 | CYP11B1 (0.49) | CYP11B1CYP11B2 | |
| SCHEMBL16834841 | 0.79 | CYP11B1 (0.49) | CYP11B1CYP11B2 | |
| SCHEMBL16834854 | 0.75 | CYP11B1 (0.53) | CYP11B1CYP11B2 | |
| SCHEMBL16834852 | 0.75 | CYP11B1 (0.53) | CYP11B1CYP11B2 | |
| SCHEMBL16834855 | 0.75 | CYP11B1 (0.53) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083605-B1 | FLUOROPHENYL PYRAZOL COMPOUNDS | LILLY CO ELI (US) | 2018-02-21 | — | — | EP | disclosed |
| EP-3083605-B1 | FLUOROPHENYL PYRAZOL COMPOUNDS | LILLY CO ELI (US) | 2018-02-21 | — | — | EP | disclosed |
| US-9499490-B2 | Fluorophenyl pyrazol compounds | ELI LILLY AND COMPANY (US) | 2016-11-22 | — | — | US | disclosed |
| US-9499490-B2 | Fluorophenyl pyrazol compounds | ELI LILLY AND COMPANY (US) | 2016-11-22 | — | — | US | disclosed |
| US-9499490-B2 | Fluorophenyl pyrazol compounds | ELI LILLY AND COMPANY (US) | 2016-11-22 | — | — | US | disclosed |
| US-20160289195-A1 | FLUOROPHENYL PYRAZOL COMPOUNDS | ELI LILLY AND COMPANY | 2016-10-06 | — | — | US | disclosed |
| US-20160289195-A1 | FLUOROPHENYL PYRAZOL COMPOUNDS | ELI LILLY AND COMPANY | 2016-10-06 | — | — | US | disclosed |
| US-20160289195-A1 | FLUOROPHENYL PYRAZOL COMPOUNDS | ELI LILLY AND COMPANY | 2016-10-06 | — | — | US | disclosed |
| WO-2015094913-A1 | FLUOROPHENYL PYRAZOL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015089800-A1 | FLUOROPHENYL PYRAZOL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2015-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160289195-A1 | FLUOROPHENYL PYRAZOL COMPOUNDS | SLCO1B3, CYP3A43, CYP4F3 | CYP11B1 40/4885CYP11B2 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.