Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 2/20 | 0.37 |
| ▸ | CIT | O14578 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16392367 | 1.00 | SPHK1 (0.40) | SPHK1SPHK2FURINCITTAAR1 | |
| SCHEMBL15692085 | 0.89 | NPY4R (0.38) | SPHK1SPHK2FURIN | |
| SCHEMBL12944390 | 0.89 | NPY4R (0.38) | SPHK1SPHK2FURIN | |
| SCHEMBL7607468 | 0.89 | NPY4R (0.38) | SPHK1SPHK2FURIN | |
| SCHEMBL20158427 | 0.89 | NPY4R (0.38) | SPHK1SPHK2FURIN | |
| SCHEMBL84332 | 0.89 | NPY4R (0.38) | SPHK1SPHK2FURIN | |
| SCHEMBL20966573 | 0.89 | SPHK1 (0.41) | SPHK1SPHK2FURINCITTAAR1 | |
| SCHEMBL20739105 | 0.89 | NPY4R (0.38) | SPHK1SPHK2FURIN | |
| SCHEMBL22315797 | 0.89 | NPY4R (0.38) | SPHK1SPHK2FURIN | |
| SCHEMBL16770343 | 0.89 | SIRT1 (0.39) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015095227-A2 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH, INC. (US) | 2015-06-25 | — | — | WO | disclosed |