Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16841015 | 1.00 | MAPT (0.46) | MAPTTP53LMNARAB9AMMP2 | |
| SCHEMBL20594637 | 0.96 | TP53 (0.47) | MAPTTP53LMNARAB9AMMP2 | |
| SCHEMBL21096319 | 0.96 | TP53 (0.47) | MAPTTP53LMNARAB9AMMP2 | |
| SCHEMBL26601876 | 0.96 | TP53 (0.47) | MAPTTP53LMNARAB9AMMP2 | |
| SCHEMBL25907978 | 0.96 | TP53 (0.47) | MAPTTP53LMNARAB9AMMP2 | |
| SCHEMBL8955714 | 0.96 | TP53 (0.47) | MAPTTP53LMNARAB9AMMP2 | |
| SCHEMBL16603409 | 0.93 | RAB9A (0.56) | MAPTTP53LMNARAB9AMMP2 | |
| SCHEMBL11599173 | 0.92 | RAB9A (0.49) | MAPTTP53LMNARAB9AMAOB | |
| SCHEMBL11502430 | 0.92 | RAB9A (0.49) | MAPTTP53LMNARAB9AMAOB | |
| SCHEMBL15583679 | 0.92 | HDAC1 (0.47) | MAPTTP53LMNARAB9AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855627-B1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-09-20 | — | — | EP | disclosed |
| US-20150175886-A1 | MESOGENIC MEDIA AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |