SCHEMBL16850132

SCHEMBL16850132

CC1(C)c2cc(-c3cc4c5ccccc5n5c6ccccc6c(c3)c45)ccc2-c2ccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccccc5)ccc43)cc21

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HDAC4 P56524 1/20 0.33
PTGER4 P35408 1/20 0.32
TSPO P30536 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16850082 0.93 KDM4E (0.41) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16842511 0.93 KDM4E (0.37) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16850101 0.93 KDM4E (0.33) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL16850109 0.93 KDM4E (0.33) KDM4EATML3MBTL1HDAC4TSPO
SCHEMBL24795804 0.92 KDM4E (0.31) KDM4EATML3MBTL1
SCHEMBL11981054 0.92 L3MBTL1 (0.46) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16842541 0.92 KDM4E (0.38) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL15625339 0.91 L3MBTL1 (0.47) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL14212267 0.90 L3MBTL1 (0.44) KDM4EATML3MBTL1HDAC4PTGER4
SCHEMBL16850061 0.89 KDM4E (0.31) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150179955-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-25 US disclosed
US-20150179955-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-25 US disclosed