Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.88 |
| ▸ | EYA2 | O00167 | 1/20 | 0.88 |
| ▸ | APP | P05067 | 1/20 | 0.88 |
| ▸ | ACE | P12821 | 1/20 | 0.88 |
| ▸ | BLM | P54132 | 2/20 | 0.82 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.82 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.82 |
| ▸ | TSHR | P16473 | 2/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.82 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.82 |
| ▸ | DRD1 | P21728 | 1/20 | 0.82 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.82 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.82 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.82 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.82 |
| ▸ | DRD3 | P35462 | 1/20 | 0.82 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.82 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Edetic Acid SCHEMBL6671722 | 1.00 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL9645089 | 1.00 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL16239366 | 1.00 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL275772 | 1.00 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Pentetic Acid SCHEMBL6241488 | 0.97 | TDP1 (0.88) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL9509453 | 0.97 | TDP1 (0.82) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL8044889 | 0.97 | TDP1 (0.82) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL8658392 | 0.97 | TDP1 (0.82) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL7791106 | 0.97 | TDP1 (0.82) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL7525860 | 0.97 | TDP1 (0.82) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927532-B2 | Therapeutic agent and diagnostic agent for mitochondrial dysfunction brain diseases | SBI PHARMACEUTICALS CO., LTD. (JP) | 2015-01-06 | — | — | US | claimed |
| US-20130011337-A1 | THERAPEUTIC AGENT AND DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES | SBI PHARMACEUTICALS CO., LTD. (JP) | 2013-01-10 | — | — | US | claimed |
| EP-2305237-A1 | THERAPEUTIC AGENT FOR MALE STERILITY | SBI ALApromo Co., Ltd. (JP) | 2011-04-06 | — | — | EP | claimed |
| US-20110065787-A1 | THERAPEUTIC AGENT FOR MALE STERILITY | SBI ALApromo., Ltd. | 2011-03-17 | — | — | US | claimed |
| EP-2305237-A1 | THERAPEUTIC AGENT FOR MALE STERILITY | SBI ALApromo Co., Ltd. (JP) | 2011-04-06 | — | — | EP | disclosed |
| US-20110065787-A1 | THERAPEUTIC AGENT FOR MALE STERILITY | SBI ALApromo., Ltd. | 2011-03-17 | — | — | US | disclosed |