Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723008 | 0.80 | KDM4E (0.53) | MEN1KMT2AMAOACTSVCTSL | |
| SCHEMBL382594 | 0.73 | GAA (0.58) | GAAMEN1KMT2APOLBCASP6 | |
| SCHEMBL16852339 | 0.73 | TSHR (0.34) | POLBTDP1NQO1KDM4EALDH1A1 | |
| SCHEMBL15583676 | 0.72 | RXFP1 (0.39) | MEN1KMT2APOLBTDP1NQO1 | |
| Carbazole SCHEMBL28117037 | 0.71 | KDM4E (0.57) | GAAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18904501 | 0.70 | TSHR (0.40) | GAAPOLBTDP1KDM4EALDH1A1 | |
| SCHEMBL15583774 | 0.68 | NQO1 (0.38) | GAAKMT2APOLBMAOANQO1 | |
| SCHEMBL18904517 | 0.68 | KDM4E (0.45) | GAAMEN1KMT2APOLBCASP6 | |
| SCHEMBL13609786 | 0.68 | PKM (0.55) | MEN1KMT2APOLBTDP1KDM4E | |
| SCHEMBL15583674 | 0.67 | PBRM1 (0.41) | ABCG2MAOANQO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249249-B2 | Light absorbing compounds for optical polymers | BAUSCH & LOMB INCORPORATED (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150175732-A1 | LIGHT ABSORBING COMPOUNDS FOR OPTICAL POLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2015-06-25 | — | — | US | disclosed |