Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.37 |
| ▸ | BCL2L11 | O43521 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15583711 | 0.87 | DPP3 (0.38) | DYRK1ANQO1KDM4ECA12CA1 | |
| SCHEMBL5454177 | 0.83 | ABCG2 (0.47) | NQO1KDM4ECHEK1WEE1MAOA | |
| SCHEMBL16852336 | 0.80 | PBRM1 (0.49) | PBRM1DYRK1ANQO1KDM4EAR | |
| SCHEMBL31085355 | 0.75 | PBRM1 (0.41) | PBRM1DYRK1ANQO1KDM4EAR | |
| SCHEMBL15583674 | 0.75 | PBRM1 (0.41) | PBRM1DYRK1ANQO1KDM4EAR | |
| SCHEMBL5457154 | 0.69 | MAOA (0.65) | MAOAACHEMAOB | |
| SCHEMBL15583675 | 0.69 | PBRM1 (0.41) | PBRM1DYRK1ANQO1KDM4ECA12 | |
| SCHEMBL14447674 | 0.66 | MAOA (0.74) | KDM4EMAOAACHEMAOB | |
| SCHEMBL4172883 | 0.65 | DYRK1A (0.60) | PBRM1DYRK1AKDM4ECA12CA9 | |
| SCHEMBL29391821 | 0.65 | DYRK1A (0.60) | PBRM1DYRK1AKDM4ECA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249249-B2 | Light absorbing compounds for optical polymers | BAUSCH & LOMB INCORPORATED (US) | 2016-02-02 | — | — | US | disclosed |
| US-9249249-B2 | Light absorbing compounds for optical polymers | BAUSCH & LOMB INCORPORATED (US) | 2016-02-02 | — | — | US | disclosed |
| US-20150175732-A1 | LIGHT ABSORBING COMPOUNDS FOR OPTICAL POLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2015-06-25 | — | — | US | disclosed |
| US-20150175732-A1 | LIGHT ABSORBING COMPOUNDS FOR OPTICAL POLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2015-06-25 | — | — | US | disclosed |