Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5985994 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL6225713 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6225420 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL6533559 | 0.74 | — | — | |
| SCHEMBL7194301 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL3358706 | 0.73 | — | — | |
| Bromide SCHEMBL7930567 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL3373043 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL6047528 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL6228407 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1231225-B1 | Method for the preparation of metallocene catalysts | TOTAL PETROCHEMICALS RES FELUY (BE) | 2011-04-06 | — | — | EP | disclosed |
| US-6777367-B2 | MIXING ALUMOXANE COCATALYST PARTICLES WITH A SUPPORT IN AN AROMATIC HYDROCARBON SOLVENT; CONTACTING WITH A DISPERSION OF METALLOCENE IN AN AROMATIC HYDROCARBON SOLVENT; WASHING WITH A PARAFFIN; DISPERSING IN VISCOUS MINERAL OIL | FINA TECHNOLOGY, INC. | 2004-08-17 | — | — | US | disclosed |
| US-20020137623-A1 | Method for the preparation of metallocene catalysts | FINA TECHNOLOGY, INC. | 2002-09-26 | — | — | US | disclosed |
| EP-1231225-A1 | Method for the preparation of metallocene catalysts | FINA TECHNOLOGY, INC. (US) | 2002-08-14 | — | — | EP | disclosed |