Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13827419 | 0.87 | PDK2 (0.39) | PDK2PGR | |
| SCHEMBL13827406 | 0.85 | PDK2 (0.37) | PDK2PGR | |
| SCHEMBL16852554 | 0.85 | PDK2 (0.34) | PDK2 | |
| SCHEMBL16852553 | 0.84 | PDK2 (0.34) | PDK2 | |
| SCHEMBL808007 | 0.84 | PDK2 (0.39) | PDK2 | |
| SCHEMBL13827556 | 0.83 | PDK2 (0.39) | PDK2PGR | |
| SCHEMBL18542369 | 0.82 | PGR (0.34) | PDK2PGR | |
| SCHEMBL18544766 | 0.82 | PDK2 (0.40) | PDK2PGR | |
| SCHEMBL18544764 | 0.82 | PGR (0.35) | PDK2PGR | |
| SCHEMBL16852525 | 0.81 | TYMS (0.32) | PDK2HSD11B1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9595681-B2 | Compounds and organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-03-14 | — | — | US | disclosed |
| US-9595681-B2 | Compounds and organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2017-03-14 | — | — | US | disclosed |
| EP-2875092-B1 | COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-20150179953-A1 | COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150179953-A1 | COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150179953-A1 | COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICES | AFF2, ETV6, PEF1 | PDK2 1521/4885HSD11B1 3576/4885PGR 2575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.