SCHEMBL16853098

SCHEMBL16853098

C[C@@H]1CN[C@@H](CN2CCOC[C@H]2C)CN1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.34
BIRC2 Q13490 6/20 0.32
XIAP P98170 5/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30491803 1.00 LTA4H (0.34) LTA4HBIRC2XIAPCA12CA1
SCHEMBL13825880 1.00 LTA4H (0.34) LTA4HBIRC2XIAPCA12CA1
Tert-Butyl Formate SCHEMBL27947052 0.85 BIRC2 (0.31) BIRC2XIAPKCNH2
Tert-Butyl Formate SCHEMBL27947051 0.85 BIRC2 (0.31) BIRC2XIAPKCNH2
SCHEMBL16723 0.80 LTA4H (0.33) LTA4HCA12CA1CA2CA9
Hydrochloric Acid SCHEMBL17003 0.79 LTA4H (0.33) LTA4HCA12CA1CA2CA9
Hydrochloric Acid SCHEMBL17159 0.79 LTA4H (0.33) LTA4HCA12CA1CA2CA9
SCHEMBL19936138 0.78 LTA4H (0.32) LTA4H
SCHEMBL22272064 0.78 LTA4H (0.32) LTA4H
SCHEMBL30701458 0.77 GAA (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023230541-A1 PIPERAZINE DERIVATIVES USEFUL IN HIV THERAPY VIIV HEALTHCARE COMPANY (US) 2023-11-30 WO disclosed
CN-109071525-B Dimeric compounds 豪夫迈·罗氏有限公司 2022-08-19 CN disclosed
WO-2015092420-A1 BICYCLIC HETEROCYCLE COMPOUNDS AND THEIR USES IN THERAPY ASTEX THERAPEUTICS LIMITED (GB) 2015-06-25 WO disclosed