SCHEMBL1685385

SCHEMBL1685385

O=c1c2cc(Br)ccc2c2cc3c(=O)c4cc(Br)ccc4c3cc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.46
TLR9 Q9NR96 1/20 0.46
PIM1 P11309 3/20 0.43
CHEK1 O14757 2/20 0.43
FLT3 P36888 2/20 0.43
METAP2 P50579 1/20 0.43
AURKA O14965 1/20 0.43
DAPK3 O43293 1/20 0.43
JAK2 O60674 1/20 0.43
PRKD3 O94806 1/20 0.43
MAP4K4 O95819 1/20 0.43
PAK4 O96013 1/20 0.43
ABL1 P00519 1/20 0.43
NTRK1 P04629 1/20 0.43
CSF1R P07333 1/20 0.43
RET P07949 1/20 0.43
MET P08581 1/20 0.43
PDGFRB P09619 1/20 0.43
FGFR1 P11362 1/20 0.43
PDGFRA P16234 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12148722 1.00 HSP90AA1 (0.46) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL29772248 1.00 HSP90AA1 (0.46) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL14873561 0.95 HSP90AA1 (0.46) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL19164173 0.89 MEN1 (0.47) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL19164101 0.88 MEN1 (0.46) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL13780231 0.88 HSP90AA1 (0.38) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL12198628 0.88 HSP90AA1 (0.38) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL19391514 0.88 CSNK2A2 (0.43) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL19164104 0.86 MEN1 (0.49) HSP90AA1TLR9PIM1CHEK1FLT3
SCHEMBL22599843 0.86 MEN1 (0.44) HSP90AA1TLR9PIM1CHEK1FLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114950159-B Preparation method of aromatic polymer separation membrane based on super acid catalysis 南京工业大学 2023-06-06 CN claimed
CN-114950159-A Preparation method of aromatic polymer separation membrane based on super-acid catalysis preparation 南京工业大学 2022-08-30 CN claimed
CN-114950159-B Preparation method of aromatic polymer separation membrane based on super acid catalysis 南京工业大学 2023-06-06 CN disclosed
CN-114950159-A Preparation method of aromatic polymer separation membrane based on super-acid catalysis preparation 南京工业大学 2022-08-30 CN disclosed
EP-1883688-B1 COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-04-11 EP disclosed
EP-2045848-B1 ORGANIC ELECTROLUMINESCENT DEVICE MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO (JP) 2017-09-27 EP disclosed
US-9461249-B2 Compounds for organic electronic devices MERCK PATENT GMBH (DE) 2016-10-04 US disclosed
US-9461249-B2 Compounds for organic electronic devices MERCK PATENT GMBH (DE) 2016-10-04 US disclosed
US-9246103-B2 Polymers and oligomers with functionalized side groups MERCK PATENT GMBH (DE) 2016-01-26 US disclosed
US-9246103-B2 Polymers and oligomers with functionalized side groups MERCK PATENT GMBH (DE) 2016-01-26 US disclosed
US-20150031896-A1 COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-01-29 US disclosed
EP-2045848-A1 ORGANIC ELECTROLUMINESCENT DEVICE MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE Idemitsu Kosan Co., Ltd. (JP) 2009-04-08 EP disclosed
WO-2009017798-A1 CONJUGATED MONOMERS AND POLYMERS AND PREPARATION AND USE THEREOF NORTHWESTERN UNIVERSITY (US) 2009-02-05 WO disclosed
WO-2009017798-A1 CONJUGATED MONOMERS AND POLYMERS AND PREPARATION AND USE THEREOF NORTHWESTERN UNIVERSITY (US) 2009-02-05 WO disclosed
US-20090036643-A1 Conjugated monomers and polymers and preparation and use thereof NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2009-02-05 US disclosed
US-20090036643-A1 Conjugated monomers and polymers and preparation and use thereof NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2009-02-05 US disclosed
US-20090036643-A1 Conjugated monomers and polymers and preparation and use thereof NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2009-02-05 US disclosed
US-20080220285-A1 Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices MERCK PATENT GMBH (DE) 2008-09-11 US disclosed
US-20080220285-A1 Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices MERCK PATENT GMBH (DE) 2008-09-11 US disclosed
WO-2007061218-A1 ORGANIC ELECTROLUMINESCENT COMPOUNDS AND DISPLAY DEVICE USING THE SAME GRACEL DISPLAY INC. (KR) 2007-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080220285-A1 Derivatives of fused aromatic systems; sublimation stability; easy to purify due to better solubilty; easy reproducibility because do not form isomers; high efficiency and high stability on use in organic electroluminescent devices TYR, DDT, PAH HSP90AA1 4155/4885TLR9 4035/4885PIM1 351/4885
US-20150031896-A1 COMPOUNDS FOR ORGANIC ELECTRONIC DEVICES TYR, TOE1, GPX1 HSP90AA1 4350/4885TLR9 3976/4885PIM1 987/4885
US-20090036643-A1 Conjugated monomers and polymers and preparation and use thereof PCNA, HMGB1, HMGB3 HSP90AA1 3815/4885TLR9 349/4885PIM1 4703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.