HMGB3

High mobility group protein B3 · O15347 · HMGB3 on Sugi Atlas →

0 patent compounds predicted against HMGB3, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to HMGB3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Clinical Evaluation of the Effect of Metformin in Sepsis PHASE3UNKNOWN
Cocoa Flavanols for Modulating Immune Response and Accelerating Recovery PHASE1/PHASE2COMPLETED
Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC PHASE2COMPLETED
Simvastatin as Inhibitor of Cell Adhesion Mediated Drug Resistance in Patients With Refractory Multiple Myeloma. PHASE2COMPLETED
MIT-001 for Prevention of CCRT-Induced OM in HNSCC Patients PHASE2ACTIVE_NOT_RECRUITING
Targeting the Tumor Microenvironment in R/M SCCHN PHASE1/PHASE2UNKNOWN
Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC) PHASE2COMPLETED
Pravastatin for Prevention of Preeclampsia PHASE1COMPLETED
EVALUATION OF SALIVARY BİOMARKER LEVELS IN SMOKING AND NON-SMOKER INDIVIDUALS WITH DIFFERENT PERIODONTAL DISEASES nanCOMPLETED
Effects of Cardiac Rehabilitation on High Mobility Group Box-1 Levels After Acute Myocardial Infarction nanCOMPLETED
Markers of Tissue Injury and Rhabdomyolysis in Patients With Major Trauma nanCOMPLETED
Post-surgery Systemic Inflammation and Neuro-immune Interactions nanCOMPLETED
Macrophage Inhibitory Factor and High-Mobility Group-1 Protein in Children Undergoing Cardiopulmonary Bypass nanCOMPLETED
The White Blood Cell Reactivity Following Surgical Trauma and Associated Regulatory Mechanisms. nanCOMPLETED
Evaluating the Relationship of Morphine Consumption and Pain-related Molecules in Hepatic Surgical Patients nanCOMPLETED
Role of High Mobility Group Box 1 as a Prognostic Biomarker in Patients Undergoing Valvular Heart Surgery nanCOMPLETED
Pravastatin Therapy in Patients With Active Crohn's Disease: A Pilot Study nanUNKNOWN
The Investigation on the Expression of High Mobility Group Protein Box-1 (HMGB1) in Peripheral Blood of Vitiligo Patients and Healthy Controls According to Clinical Features, Treatment and Disease Activity nanCOMPLETED
The Neuroprotective Effect of Dexmedetomidine Preserving Brain Functional Connectivity in Elderly Patients nanCOMPLETED
Anti-C1s, Anti-HMGB1 and Anti-C1q Autoantibodies in Systemic Lupus Erythematosus (DYSALARM-322) nanRECRUITING
Effect of Atorvastatin (Lipitor) on Gene Expression in People With Vascular Disease nanCOMPLETED
Histochemical Study of Vitiligo in Sohag University Hospital Patients nanUNKNOWN
Detection of Circulating Biomarkers of Immunogenic Cell Death nanCOMPLETED
Inflammatory Biomarkers of Pediatric Pulmonary Hypertension nanCOMPLETED
A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study nanCOMPLETED
Pro-inflammatory Role of Blood Platelets in Critically Ill Patients With Septic Shock. nanCOMPLETED
Galectin-3 Binding Protein in Cardiovascular Disease and Chronic Heart Failure nanCOMPLETED
Implication of Long Non-coding RNA CCDC144NL-AS1/Micro RNA-143-3p Axis Expression Level as Novel Signature in Colorectal Cancer nanCOMPLETED
Epidemiology of Atherosclerosis nanCOMPLETED
Assessment of Vitamin D Supplementation and Immune Function nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a HMGB3 binder may also engage these)

ProteinNameSimilarity
O54879 1.000 O54879 →
P40618 1.000 P40618 →
Q32L31 1.000 Q32L31 →
P10103 1.000 P10103 →
B0CM99 1.000 B0CM99 →
P26584 1.000 P26584 →
Q9YH06 1.000 Q9YH06 →
P63159 1.000 P63159 →
HMGB1 High mobility group protein B1 1.000 landscape →
Q08IE6 1.000 Q08IE6 →
B2RPK0 1.000 B2RPK0 →
P17741 1.000 P17741 →
P12682 1.000 P12682 →
P07156 1.000 P07156 →
P40673 1.000 P40673 →
P30681 0.999 P30681 →
P63158 0.999 P63158 →
Q6YKA4 0.999 Q6YKA4 →
B1MTB0 0.999 B1MTB0 →
A9RA84 0.999 A9RA84 →
Q4R844 0.999 Q4R844 →
HMGB2 High mobility group protein B2 0.998 landscape →
P52925 0.997 P52925 →
P07746 0.995 P07746 →
P40644 0.995 P40644 →
Q06943 0.994 Q06943 →
P11873 0.993 P11873 →
Q05783 0.992 Q05783 →
P40625 0.990 P40625 →
P0CO24 0.989 P0CO24 →