Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889159 | 1.00 | TSHR (0.64) | TSHRLMNACYP2C9CES2CES1 | |
| SCHEMBL15484232 | 1.00 | TSHR (0.64) | TSHRLMNACYP2C9CES2CES1 | |
| SCHEMBL15484298 | 1.00 | TSHR (0.64) | TSHRLMNACYP2C9CES2CES1 | |
| SCHEMBL2154470 | 1.00 | TSHR (0.64) | TSHRLMNACYP2C9CES2CES1 | |
| SCHEMBL15337087 | 1.00 | TSHR (0.64) | TSHRLMNACYP2C9CES2CES1 | |
| SCHEMBL10795387 | 1.00 | TSHR (0.64) | TSHRLMNACYP2C9CES2CES1 | |
| SCHEMBL13888941 | 1.00 | TSHR (0.64) | TSHRLMNACYP2C9CES2CES1 | |
| SCHEMBL13375682 | 0.96 | TSHR (0.60) | TSHRLMNACYP2C9CES2CES1 | |
| SCHEMBL3089221 | 0.96 | — | — | |
| SCHEMBL3089224 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9531004-B2 | Multifunctional hybrid coatings for electrodes made by atomic layer deposition techniques | GM Global Technology Operations LLC (US) | 2016-12-27 | — | — | US | disclosed |
| US-20150180023-A1 | MULTIFUNCTIONAL HYBRID COATINGS FOR ELECTRODES MADE BY ATOMIC LAYER DEPOSITION TECHNIQUES | GM Global Technology Operations LLC (US) | 2015-06-25 | — | — | US | disclosed |