Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.47 |
| ▸ | PREP | P48147 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175619 | 0.96 | POLB (0.53) | POLBSMN1; SMN2NPC1RAB9AAGTR2 | |
| SCHEMBL9175614 | 0.96 | POLB (0.53) | POLBSMN1; SMN2NPC1RAB9AAGTR2 | |
| SCHEMBL9960832 | 0.96 | POLB (0.53) | POLBSMN1; SMN2NPC1RAB9AAGTR2 | |
| SCHEMBL16857378 | 0.96 | POLB (0.53) | POLBSMN1; SMN2NPC1RAB9AAGTR2 | |
| SCHEMBL17024445 | 0.96 | POLB (0.53) | POLBSMN1; SMN2NPC1RAB9AAGTR2 | |
| SCHEMBL16857280 | 0.96 | POLB (0.53) | POLBSMN1; SMN2NPC1RAB9AAGTR2 | |
| SCHEMBL16857358 | 0.96 | POLB (0.53) | POLBSMN1; SMN2NPC1RAB9AAGTR2 | |
| SCHEMBL9175610 | 0.96 | POLB (0.53) | POLBSMN1; SMN2NPC1RAB9AAGTR2 | |
| SCHEMBL17024448 | 0.96 | POLB (0.53) | POLBSMN1; SMN2NPC1RAB9AAGTR2 | |
| SCHEMBL16857510 | 0.87 | POLB (0.52) | POLBSMN1; SMN2NPC1RAB9APREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2889288-B1 | METHOD FOR PRODUCING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID DERIVATIVE, AND METHOD FOR PURIFYING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID | API CORP (JP) | 2018-07-25 | — | — | EP | disclosed |
| US-9981984-B2 | Method for producing cis-5-hydroxy-2-piperidinecarboxylic acid derivative, and method for purifying cis-5-hydroxy-2-piperidinecarboxylic acid | API CORPORATION (JP) | 2018-05-29 | — | — | US | disclosed |
| US-20150239906-A1 | Method for Producing cis-5-hydroxy-2-piperidinecarboxylic Acid Derivative, and Method for Purifying cis-5-hydroxy-2-piperidinecarboxylic Acid | UBE CORPORATION (JP) | 2015-08-27 | — | — | US | disclosed |
| EP-2889288-A1 | METHOD FOR PRODUCING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID DERIVATIVE, AND METHOD FOR PURIFYING cis-5-HYDROXY-2-PIPERIDINECARBOXYLIC ACID | API Corporation (JP) | 2015-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239906-A1 | Method for Producing cis-5-hydroxy-2-piperidinecarboxylic Acid Derivative, and Method for Purifying cis-5-hydroxy-2-piperidinecarboxylic Acid | HCAR2, HCAR1, C5 | POLB 3432/4885SMN1; SMN2 3680/4885NPC1 3080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.