SCHEMBL1685755

SCHEMBL1685755

C=C(CCC1CO1)C(=O)OCCCC

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.38
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
HCAR2 Q8TDS4 1/20 0.33
ESR1 P03372 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10681047 0.91 ALDH1A1 (0.44) TSHRALDH1A1SMN1; SMN2TDP1
SCHEMBL8439320 0.88 ALDH1A1 (0.41) TSHRALDH1A1SMN1; SMN2HPGDTDP1
SCHEMBL4370789 0.87 ALDH1A1 (0.44) ALDH1A1
SCHEMBL2119578 0.85 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL20269205 0.84 ALDH1A1 (0.44) TSHRALDH1A1SMN1; SMN2TDP1
SCHEMBL1685769 0.84 TSHR (0.45) TSHRALDH1A1SMN1; SMN2HPGDATM
SCHEMBL2906191 0.84 ALDH1A1 (0.46) TSHRALDH1A1
SCHEMBL6560347 0.84 ALDH1A1 (0.37) ALDH1A1
SCHEMBL9453047 0.83 ALDH1A1 (0.41) TSHRALDH1A1
SCHEMBL8007275 0.82 ALDH1A1 (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2308081-A1 DUAL DAMASCENE VIA FILLING COMPOSITION AZ Electronic Materials USA Corp. (US) 2011-04-13 EP disclosed
WO-2010007477-A1 DUAL DAMASCENE VIA FILLING COMPOSITION AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-01-21 WO disclosed
US-20100015550-A1 DUAL DAMASCENE VIA FILLING COMPOSITION AZ ELECTRONIC MATERIALS USA CORP. 2010-01-21 US disclosed
US-6852197-B2 Wet strong tissue paper AKZO NOBEL NV (NL) 2005-02-08 US disclosed
US-6702923-B1 SOFT TISSUE PAPER; USING CROSSLINKED CATIONIC POLYAMIDE HAVING HYDROPHOBIC SIDE CHAINS AKZO NOBEL NV (NL) 2004-03-09 US disclosed
EP-1242466-B1 WET STRENGTH AGENT AND METHOD FOR PRODUCTION THEREOF AKZO NOBEL NV (NL) 2004-01-21 EP disclosed
EP-1316565-A2 Wet strength agent and method for production thereof Eka Chemicals AB (SE) 2003-06-04 EP disclosed
US-20030024667-A1 Wet strong tissue paper WALLENIUS HANS (SE) 2003-02-06 US disclosed
EP-1242466-A1 WET STRENGTH AGENT AND METHOD FOR PRODUCTION THEREOF Akzo Nobel N.V. (NL) 2002-09-25 EP disclosed
US-20020096281-A1 Wet-strong tissue paper AKZO NOBEL NV (NL) 2002-07-25 US disclosed
WO-2001036491-A1 WET STRENGTH AGENT AND METHOD FOR PRODUCTION THEREOF AKZO NOBEL N.V. (NL) 2001-05-25 WO disclosed
US-4764447-A UNSATURATED ESTER MONOMER RICOH CO., LTD. (JP) 1988-08-16 US disclosed