Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28148537 | 0.98 | ESR1 (0.53) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL3314631 | 0.83 | ESR1 (0.61) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL8596721 | 0.83 | ESR1 (0.61) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL14148460 | 0.82 | ESR1 (0.74) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL9310985 | 0.81 | ESR1 (0.55) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL9317931 | 0.80 | ESR1 (0.56) | ESR1ESR2CYP19A1PTGS2TP53 | |
| SCHEMBL9275462 | 0.79 | ESR1 (0.53) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL22022231 | 0.78 | ESR1 (0.70) | ESR1ESR2CYP19A1PGRCYP3A4 | |
| SCHEMBL3841100 | 0.77 | CES1 (0.43) | ESR1ESR2CYP19A1PTGS2CYP3A4 | |
| SCHEMBL3841099 | 0.77 | CES1 (0.43) | ESR1ESR2CYP19A1PTGS2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2889643-B1 | Multiple technologies composite scintillation detector device | NUCTECH CO LTD (CN) | 2016-10-05 | — | — | EP | disclosed |
| US-9322933-B2 | Multiple technologies composite scintillation detector device | NUCTECH COMPANY LIMITED (CN) | 2016-04-26 | — | — | US | disclosed |
| US-20150185335-A1 | MULTIPLE TECHNOLOGIES COMPOSITE SCINTILLATION DETECTOR DEVICE | TSINGHUA UNIVERSITY (CN) | 2015-07-02 | — | — | US | disclosed |
| EP-2889643-A1 | Multiple technologies composite scintillation detector device | Nuctech Company Limited (CN) | 2015-07-01 | — | — | EP | disclosed |