Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596721 | 0.87 | ESR1 (0.61) | ESR1ESR2CYP19A1ATMPTGS2 | |
| SCHEMBL3314631 | 0.87 | ESR1 (0.61) | ESR1ESR2CYP19A1ATMPTGS2 | |
| SCHEMBL9275462 | 0.83 | ESR1 (0.53) | ESR1ESR2CYP19A1ATMPTGS2 | |
| SCHEMBL28148537 | 0.83 | ESR1 (0.53) | ESR1ESR2CYP19A1ATMPTGS2 | |
| SCHEMBL9310232 | 0.81 | ESR1 (0.58) | ESR1ESR2CYP19A1ATMPTGS2 | |
| SCHEMBL16857587 | 0.81 | ESR1 (0.57) | ESR1ESR2CYP19A1ATMPTGS2 | |
| SCHEMBL25455453 | 0.80 | PTGS2 (0.42) | ESR1ESR2CYP19A1ATMPTGS2 | |
| SCHEMBL641477 | 0.80 | ESR1 (0.80) | ESR1ESR2CYP19A1PTGS2PGR | |
| SCHEMBL585024 | 0.80 | ESR1 (0.55) | ESR1ESR2CYP19A1ATMPTGS2 | |
| SCHEMBL13044536 | 0.78 | ESR1 (0.77) | ESR1ESR2CYP19A1PTGS2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327191-A | THEN AMINATING | RHONE-POULENC INDUSTRIES (FR) | 1982-04-27 | — | — | US | claimed |
| EP-0025385-A1 | Preparation of anion-exchange resins by bromination of vinylaromatic polymers, and products obtained | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-03-18 | — | — | EP | claimed |
| CN-108137569-B | Substituted morpholine derivatives having anti-pain activity | 埃斯蒂文制药股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-106832299-A | A kind of derivative modified organosilicon damping additives of DOPO and preparation method and application | 中国科学院化学研究所 | 2017-06-13 | — | — | CN | disclosed |
| CN-103313599-B | Substituted 4- (arylamino) selenophenopyrimidine compounds and methods of use thereof | KASINA LAILA INNOVA PHARMACEUTICALS PRIVATE LTD. (IN) | 2016-03-23 | — | — | CN | disclosed |
| CN-105061768-A | Preparation method for epoxy blocking side chain vinyl methyl phenyl silicone oil | JIAXING UNITED CHEMICAL CO LTD | 2015-11-18 | — | — | CN | disclosed |
| CN-103254029-B | Method for synthesizing 2-iodoallyl fluorine compound | ZHEJIANG UNIVERSITY (CN) | 2014-10-08 | — | — | CN | disclosed |
| US-5326489-A | Sulfonated polymer | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0523300-B1 | Electrorheological fluids | NIPPON CATALYTIC CHEM IND (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0523300-A1 | Electrorheological fluids | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |
| US-4551502-A | Macromolecular complexes of amidocarbonylic water-soluble polymers and square platinous and equivalent organometallics | HOWELL BOBBY A | 1985-11-05 | — | — | US | disclosed |
| US-4405757-A | Macromolecular complexes of amidocarbonylic water-soluble polymers and square planar platinous and equivalent organometallics | HOWELL BOBBY A | 1983-09-20 | — | — | US | disclosed |
| EP-0025385-B1 | PREPARATION OF ANION-EXCHANGE RESINS BY BROMINATION OF VINYLAROMATIC POLYMERS, AND PRODUCTS OBTAINED | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-05-11 | — | — | EP | disclosed |
| EP-0025385-A1 | Preparation of anion-exchange resins by bromination of vinylaromatic polymers, and products obtained | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-03-18 | — | — | EP | disclosed |