Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 4/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857762 | 0.94 | EGLN1 (0.76) | EGLN1MGLL | |
| SCHEMBL16857920 | 0.89 | EGLN1 (0.52) | EGLN1 | |
| SCHEMBL16857891 | 0.88 | EGLN1 (0.49) | EGLN1MGLLKDM4C | |
| SCHEMBL3031299 | 0.87 | EGLN1 (0.87) | EGLN1 | |
| SCHEMBL16857819 | 0.86 | EGLN1 (0.48) | EGLN1MGLL | |
| SCHEMBL16857845 | 0.84 | EGLN1 (0.46) | EGLN1MGLLKDM4CSPR | |
| SCHEMBL16857907 | 0.83 | EGLN1 (0.48) | EGLN1MGLLKDM4CSPR | |
| SCHEMBL16857776 | 0.83 | EGLN1 (0.46) | EGLN1 | |
| SCHEMBL16857873 | 0.83 | EGLN1 (0.60) | EGLN1MGLL | |
| SCHEMBL16857894 | 0.83 | EGLN1 (0.60) | EGLN1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |