Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 17/20 | 0.76 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857728 | 0.94 | EGLN1 (0.66) | EGLN1MGLL | |
| SCHEMBL16857894 | 0.89 | EGLN1 (0.60) | EGLN1MGLL | |
| SCHEMBL16857873 | 0.89 | EGLN1 (0.60) | EGLN1MGLL | |
| SCHEMBL16857719 | 0.89 | EGLN1 (0.59) | EGLN1 | |
| SCHEMBL16857816 | 0.89 | EGLN1 (0.59) | EGLN1MGLL | |
| SCHEMBL16857786 | 0.88 | EGLN1 (0.57) | EGLN1 | |
| SCHEMBL3031524 | 0.86 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL16857726 | 0.86 | EGLN1 (0.56) | EGLN1 | |
| SCHEMBL16857773 | 0.86 | EGLN1 (0.56) | EGLN1MGLL | |
| SCHEMBL16857913 | 0.86 | EGLN1 (0.57) | EGLN1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |