Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 14/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857699 | 0.92 | EGLN1 (0.56) | EGLN1KDM4ELMNAHSD17B10 | |
| SCHEMBL16857755 | 0.91 | EGLN1 (0.52) | EGLN1ROCK2MMP13 | |
| SCHEMBL16857726 | 0.91 | EGLN1 (0.56) | EGLN1 | |
| SCHEMBL16857786 | 0.91 | EGLN1 (0.57) | EGLN1MMP13 | |
| SCHEMBL16857740 | 0.90 | EGLN1 (0.50) | EGLN1KDM4ELMNAHSD17B10 | |
| SCHEMBL16857773 | 0.89 | EGLN1 (0.56) | EGLN1MMP13 | |
| SCHEMBL16857897 | 0.89 | EGLN1 (0.51) | EGLN1ROCK2 | |
| SCHEMBL16857825 | 0.89 | EGLN1 (0.51) | EGLN1ROCK2ROCK1 | |
| SCHEMBL3030163 | 0.88 | EGLN1 (0.69) | EGLN1 | |
| SCHEMBL16857778 | 0.87 | EGLN1 (0.53) | EGLN1KDM4ELMNAHSD17B10MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |