Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 15/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857757 | 0.91 | EGLN1 (0.44) | EGLN1ITGB3ITGA2B | |
| SCHEMBL16857865 | 0.90 | EGLN1 (0.41) | EGLN1ITGB3ITGA2B | |
| SCHEMBL16857804 | 0.90 | EGLN1 (0.49) | EGLN1ITGB3ITGA2BABL1SRC | |
| SCHEMBL16857718 | 0.89 | EGLN1 (0.46) | EGLN1ITGB3ITGA2B | |
| SCHEMBL16857750 | 0.88 | IP6K1 (0.47) | EGLN1ITGB3ITGA2B | |
| SCHEMBL3032883 | 0.86 | EGLN1 (0.57) | EGLN1 | |
| SCHEMBL16857820 | 0.85 | EGLN1 (0.46) | EGLN1ITGB3ITGA2B | |
| SCHEMBL16857908 | 0.85 | EGLN1 (0.51) | EGLN1ITGB3ITGA2BABL1SRC | |
| SCHEMBL16857835 | 0.84 | EGLN1 (0.44) | EGLN1ITGB3ITGA2B | |
| SCHEMBL16857826 | 0.84 | EGLN1 (0.41) | EGLN1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |