Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.46 |
| ▸ | PDE9A | O76083 | 4/20 | 0.43 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857750 | 0.91 | IP6K1 (0.47) | EGLN1IP6K1ITGB3ITGA2B | |
| SCHEMBL16857738 | 0.89 | EGLN1 (0.42) | EGLN1ITGB3ITGA2B | |
| SCHEMBL16857826 | 0.88 | EGLN1 (0.41) | EGLN1IP6K1ITGB3ITGA2B | |
| SCHEMBL16857811 | 0.88 | MMP13 (0.45) | EGLN1IP6K1ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL3038773 | 0.87 | EGLN1 (0.56) | EGLN1 | |
| SCHEMBL16857757 | 0.85 | EGLN1 (0.44) | EGLN1PDE9AMGLLITGB3ITGA2B | |
| SCHEMBL16857835 | 0.85 | EGLN1 (0.44) | EGLN1PDE9AIP6K1ITGB3ITGA2B | |
| SCHEMBL16857804 | 0.84 | EGLN1 (0.49) | EGLN1ITGB3ITGA2B | |
| SCHEMBL16857865 | 0.84 | EGLN1 (0.41) | EGLN1ITGB3ITGA2B | |
| SCHEMBL16857888 | 0.83 | EGLN1 (0.52) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |