Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857874 | 0.91 | EGLN1 (0.52) | EGLN1 | |
| SCHEMBL16857883 | 0.88 | EGLN1 (0.53) | EGLN1 | |
| SCHEMBL3033393 | 0.86 | EGLN1 (0.78) | EGLN1 | |
| SCHEMBL16551670 | 0.86 | EGLN1 (0.69) | EGLN1 | |
| SCHEMBL16857722 | 0.86 | EGLN1 (0.46) | EGLN1 | |
| SCHEMBL16857901 | 0.85 | EGLN1 (0.44) | EGLN1 | |
| SCHEMBL16857812 | 0.85 | EGLN1 (0.49) | EGLN1 | |
| SCHEMBL16857789 | 0.83 | EGLN1 (0.48) | EGLN1 | |
| SCHEMBL13261530 | 0.83 | EGLN1 (0.75) | EGLN1 | |
| SCHEMBL16857856 | 0.82 | EGLN1 (0.48) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |