Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 2/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 16/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3032298 | 0.88 | EGLN1 (0.64) | EGLN1 | |
| SCHEMBL16857823 | 0.86 | EGLN1 (0.47) | SPREGLN1 | |
| SCHEMBL16857699 | 0.83 | EGLN1 (0.56) | EGLN1 | |
| SCHEMBL16857824 | 0.82 | EGLN1 (0.44) | SPREGLN1 | |
| SCHEMBL16857877 | 0.82 | EGLN1 (0.47) | SPREGLN1 | |
| SCHEMBL16857775 | 0.81 | EGLN1 (0.49) | EGLN1KDM4C | |
| SCHEMBL16857869 | 0.81 | EGLN1 (0.47) | EGLN1 | |
| SCHEMBL16857708 | 0.81 | MGLL (0.45) | EGLN1 | |
| SCHEMBL16857875 | 0.81 | EGLN1 (0.47) | EGLN1 | |
| SCHEMBL16857832 | 0.81 | EGLN1 (0.58) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |