Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 17/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857766 | 0.93 | EGLN1 (0.52) | EGLN1MGLL | |
| SCHEMBL16857775 | 0.92 | EGLN1 (0.49) | EGLN1MGLL | |
| SCHEMBL16857729 | 0.91 | EGLN1 (0.44) | EGLN1MGLL | |
| SCHEMBL16857740 | 0.90 | EGLN1 (0.50) | EGLN1CHEK2 | |
| SCHEMBL16857798 | 0.90 | EGLN1 (0.49) | EGLN1 | |
| SCHEMBL16857855 | 0.90 | EGLN1 (0.48) | EGLN1MGLL | |
| SCHEMBL16857825 | 0.89 | EGLN1 (0.51) | EGLN1 | |
| SCHEMBL16857749 | 0.89 | EGLN1 (0.45) | EGLN1 | |
| SCHEMBL16857887 | 0.88 | EGLN1 (0.48) | EGLN1MGLL | |
| SCHEMBL16857863 | 0.87 | EGLN1 (0.42) | EGLN1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |