Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 15/20 | 0.39 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857735 | 0.92 | EGLN1 (0.40) | EGLN1MGLL | |
| SCHEMBL16857831 | 0.86 | EGLN1 (0.46) | EGLN1 | |
| SCHEMBL16857717 | 0.84 | TNKS (0.48) | EGLN1 | |
| SCHEMBL16857734 | 0.84 | EGLN1 (0.51) | EGLN1MGLLKDM4C | |
| SCHEMBL16857710 | 0.84 | EGLN1 (0.40) | EGLN1KDM4C | |
| SCHEMBL16857803 | 0.84 | EGLN1 (0.51) | EGLN1KDM4C | |
| SCHEMBL3037073 | 0.84 | EGLN1 (0.55) | EGLN1 | |
| SCHEMBL16857836 | 0.84 | EGLN1 (0.39) | EGLN1MGLLKDM4CSPR | |
| SCHEMBL16857876 | 0.82 | EGLN1 (0.45) | EGLN1MGLLKDM4C | |
| SCHEMBL16857800 | 0.82 | EGLN1 (0.42) | EGLN1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |