SCHEMBL1685807

SCHEMBL1685807

O=C(CCCCl)CCCCl

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
ACE P12821 1/20 0.35
FAAH O00519 3/20 0.33
BBOX1 O75936 2/20 0.32
LMNA P02545 2/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
TP53 P04637 1/20 0.30
FOLH1 Q04609 1/20 0.30
NFKB1 P19838 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6011836 0.94 MAPT (0.39) TSHRTDP1ALDH1A1MAPTKMT2A
SCHEMBL6011904 0.90 MAPT (0.40) TSHRTDP1ALDH1A1MAPTKMT2A
SCHEMBL28696059 0.87 MAPT (0.44) TSHRTDP1ALDH1A1MAPTKMT2A
SCHEMBL28696440 0.87 MAPT (0.44) TSHRTDP1ALDH1A1MAPTKMT2A
SCHEMBL28690025 0.87 MAPT (0.44) TSHRTDP1ALDH1A1MAPTKMT2A
SCHEMBL28684308 0.87 MAPT (0.44) TSHRTDP1ALDH1A1MAPTKMT2A
SCHEMBL10696543 0.87 MAPT (0.44) TSHRTDP1ALDH1A1MAPTKMT2A
SCHEMBL2418248 0.87
SCHEMBL14842097 0.86
SCHEMBL10972287 0.86 ALDH1A1 (0.52) TSHRTDP1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119875052-A Ion polymer based on flexible main chain, anion exchange membrane and preparation method thereof 武汉轻工大学 2025-04-25 CN claimed
CN-115724728-B Synthesis process of 1, 7-dichloro-4-heptanone 常州沃腾化工科技有限公司 2024-06-21 CN claimed
CN-116514818-A Preparation method of piracy carnitinib intermediate 诚弘制药(威海)有限责任公司 2023-08-01 CN claimed
CN-115724728-A Synthesis process of 1, 7-dichloro-4-heptanone 常州沃腾化工科技有限公司 2023-03-03 CN claimed
CN-114058173-A Process and composition for producing flexible polyurethane foams 赢创运营有限公司 2022-02-18 CN claimed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US claimed
CN-119875052-B Ion polymer based on flexible main chain, anion exchange membrane and preparation method thereof 武汉轻工大学 2025-06-27 CN disclosed
WO-2025137516-A1 FLUORINATED MONOMERS, ANION EXCHANGE POLYMERS AND METHODS OF MAKING THE SAME THE CHEMOURS COMPANY FC, LLC (US) 2025-06-26 WO disclosed
CN-119875052-A Ion polymer based on flexible main chain, anion exchange membrane and preparation method thereof 武汉轻工大学 2025-04-25 CN disclosed
CN-119875052-A Ion polymer based on flexible main chain, anion exchange membrane and preparation method thereof 武汉轻工大学 2025-04-25 CN disclosed
US-20250129096-A1 ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER BOEHRINGER INGELHEIM INTL GMBH CORP (DE) 2025-04-24 US disclosed
EP-4441054-A1 ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER Boehringer Ingelheim International GmbH (DE) 2024-10-09 EP disclosed
CN-115724728-B Synthesis process of 1, 7-dichloro-4-heptanone 常州沃腾化工科技有限公司 2024-06-21 CN disclosed
EP-0345711-A2 Process for the preparation of pyrrolizine derivatives SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1989-12-13 EP disclosed
EP-0345712-A1 Pyrrolizine derivate and its manufacture SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1989-12-13 EP disclosed
US-4141910-A PLASTICIZERS, OXIDIZERS ROCKWELL INTERNATIONAL CORPORATION (US) 1979-02-27 US disclosed
US-4125552-A FROM A HALIDE, AMMONIA, HYDROCARBYLAMINE, HYDROGEN SULFIDE AND SULFUR DOW CORNING CORPORATION (US) 1978-11-14 US disclosed
US-4082790-A ORGANIC HALIDE, HYDROGEN SULFIDE, AMMONIA OR AMINE, POLAR SOLVENT DOW CORNING CORPORATION (US) 1978-04-04 US disclosed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US disclosed
US-4009208-A N,N'-HEPTAMETHYLENEBIS(4-METHOXYBENZAMIDE) STERLING DRUG INC. (US) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129096-A1 ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER KRAS, NRAS, TP53 TSHR 1062/4885TDP1 1857/4885ALDH1A1 2310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.