Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28334716 | 0.88 | CES2 (0.39) | SMN1; SMN2CES2CES1GAATSHR | |
| SCHEMBL28967581 | 0.80 | — | — | |
| SCHEMBL1635048 | 0.80 | CYP1A2 (0.38) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL29449985 | 0.80 | CES2 (0.43) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL336394 | 0.80 | CES2 (0.43) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL30787975 | 0.77 | CES2 (0.32) | CES2CES1HTTMAPT | |
| SCHEMBL8652422 | 0.77 | TSHR (0.47) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL11049701 | 0.77 | CES2 (0.32) | CES2CES1HTTMAPT | |
| Fluoride SCHEMBL10713010 | 0.77 | CES2 (0.42) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 | |
| SCHEMBL10454071 | 0.77 | CES2 (0.42) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150185614-A1 | ORGANIC BOTTOM ANTIREFLECTIVE COATING COMPOSITION FOR NANOLITHOGRAPHY | DUPONT SPECIALTY MATERIALS KOREA LTD (KR) | 2015-07-02 | — | — | US | disclosed |