Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.70 |
| ▸ | MMP2 | P08253 | 3/20 | 0.59 |
| ▸ | YARS1 | P54577 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | CSK | P41240 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29487634 | 0.88 | SLC7A5 (0.61) | SLC7A5MMP2YARS1PTGS1ERAP2 | |
| SCHEMBL28718171 | 0.88 | SLC7A5 (0.61) | SLC7A5MMP2YARS1PTGS1ERAP2 | |
| SCHEMBL24130707 | 0.85 | SLC7A5 (0.58) | SLC7A5MMP2YARS1OPRD1 | |
| SCHEMBL16860710 | 0.85 | SLC7A5 (0.66) | SLC7A5MMP2YARS1PTGS1ERAP2 | |
| Tyrosine SCHEMBL1581 | 0.83 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL11520041 | 0.83 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL11676367 | 0.83 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL638520 | 0.83 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL20787 | 0.83 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Tyrosine SCHEMBL11520027 | 0.83 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3087094-B1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | POLYPHOR AG (CH) | 2022-06-01 | — | — | EP | disclosed |
| US-10273267-B2 | Beta-hairpin peptidomimetics as selective elastase inhibitors | POLYPHOR AG (CH) | 2019-04-30 | — | — | US | disclosed |
| US-20160333053-A1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | POLYPHOR AG (CH) | 2016-11-17 | — | — | US | disclosed |
| EP-3087094-A1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | Polyphor AG (CH) | 2016-11-02 | — | — | EP | disclosed |
| WO-2015096873-A1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | POLYPHOR AG (CH) | 2015-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160333053-A1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | SERPINB1, ELANE, XPNPEP1 | SLC7A5 1527/4885MMP2 387/4885YARS1 1743/4885 |
| US-10273267-B2 | Beta-hairpin peptidomimetics as selective elastase inhibitors | SERPINB1, ELANE, XPNPEP1 | SLC7A5 1527/4885MMP2 387/4885YARS1 1743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.