Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 14/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18387434 | 0.85 | NQO2 (0.81) | NQO2MAPTRAB9ATHRBBLM | |
| SCHEMBL23589538 | 0.82 | NQO2 (0.74) | NQO2MAPTRAB9ATHRBBLM | |
| SCHEMBL19988780 | 0.82 | NQO2 (0.75) | NQO2MAPTRAB9AKDM4EGAA | |
| SCHEMBL18387431 | 0.81 | NQO2 (0.78) | NQO2MAPTRAB9ATHRBBLM | |
| SCHEMBL18387453 | 0.81 | NQO2 (0.73) | NQO2MAPTRAB9ATHRBBLM | |
| SCHEMBL23589537 | 0.80 | NQO2 (0.68) | NQO2MAPTRAB9ATHRBBLM | |
| SCHEMBL5798945 | 0.79 | NQO2 (0.81) | NQO2MAPTRAB9ATHRBBLM | |
| SCHEMBL31689762 | 0.79 | NQO2 (1.00) | NQO2MAPTRAB9ATHRBBLM | |
| SCHEMBL23589546 | 0.78 | NQO2 (0.64) | NQO2MAPTRAB9ATHRBBLM | |
| SCHEMBL23612601 | 0.78 | NQO2 (0.70) | NQO2MAPTRAB9ATHRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053205-B2 | Phenazine derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-07-06 | — | — | US | disclosed |
| US-20180312473-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2018-11-01 | — | — | US | disclosed |
| WO-2018152436-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF RESEARCH FOUNDATION, INCORPORATED (US) | 2018-08-23 | — | — | WO | disclosed |
| US-9856225-B2 | Substituted phenazines as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-01-02 | — | — | US | disclosed |
| US-9856225-B2 | Substituted phenazines as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-01-02 | — | — | US | disclosed |
| WO-2017011730-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2017-01-19 | — | — | WO | disclosed |
| WO-2017011730-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2017-01-19 | — | — | WO | disclosed |
| US-20160355487-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160355487-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160355487-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2016-12-08 | — | — | US | disclosed |
| EP-3086791-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | University of Florida Research Foundation, Inc. (US) | 2016-11-02 | — | — | EP | disclosed |
| WO-2015100331-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-07-02 | — | — | WO | disclosed |
| WO-2015100331-A2 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312473-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | ROS1, NOX4, NOX5 | NQO2 136/4885MAPT 2461/4885RAB9A 1448/4885 |
| US-11053205-B2 | Phenazine derivatives as antimicrobial agents | ROS1, NOX4, PRDX3 | NQO2 172/4885MAPT 2601/4885RAB9A 1669/4885 |
| US-20160355487-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | ROS1, NOX4, NOX5 | NQO2 349/4885MAPT 3475/4885RAB9A 2114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.