Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10344937 | 0.89 | HTR6 (1.00) | HTR6 | |
| SCHEMBL10345055 | 0.84 | HTR6 (1.00) | HTR6 | |
| SCHEMBL10344829 | 0.84 | HTR6 (0.81) | HTR6 | |
| SCHEMBL10344280 | 0.83 | HTR6 (1.00) | HTR6 | |
| SCHEMBL10344818 | 0.82 | HTR6 (1.00) | HTR6 | |
| Hydrochloric Acid SCHEMBL10323779 | 0.82 | HTR6 (0.98) | HTR6 | |
| SCHEMBL10346508 | 0.82 | HTR6 (1.00) | HTR6 | |
| SCHEMBL10344932 | 0.79 | HTR6 (1.00) | HTR6 | |
| SCHEMBL10344870 | 0.79 | HTR6 (1.00) | HTR6 | |
| SCHEMBL11954756 | 0.79 | HTR6 (0.81) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9067949-B2 | Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-HT6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia | ALBANY MOLECULAR RESEARCH, INC. (US) | 2015-06-30 | — | — | US | disclosed |