Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 17/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16864409 | 0.90 | QPCT (0.46) | QPCTTP53 | |
| SCHEMBL1444476 | 0.87 | QPCT (0.60) | QPCTALDH1A1RAB9AHSD17B10QPCTL | |
| SCHEMBL1444692 | 0.87 | QPCT (0.60) | QPCTALDH1A1RAB9AHSD17B10QPCTL | |
| SCHEMBL1444480 | 0.87 | QPCT (0.60) | QPCTALDH1A1RAB9AHSD17B10QPCTL | |
| SCHEMBL29410482 | 0.87 | QPCT (0.60) | QPCTALDH1A1RAB9AHSD17B10QPCTL | |
| SCHEMBL16864406 | 0.85 | QPCT (0.43) | QPCTQPCTL | |
| SCHEMBL12819597 | 0.83 | QPCT (0.68) | QPCTALDH1A1RAB9AHSD17B10TP53 | |
| SCHEMBL12819253 | 0.83 | QPCT (0.68) | QPCTALDH1A1RAB9AHSD17B10TP53 | |
| SCHEMBL12814445 | 0.81 | QPCT (0.57) | QPCTTP53 | |
| SCHEMBL1443993 | 0.78 | QPCT (0.62) | QPCTQPCTL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475428-B1 | HETEROCYLCIC DERIVATIVES AS INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2015-07-01 | — | — | EP | disclosed |